Location [1]
Protein [2]
Delta-like protein 4
Synonyms [1]
hdelta2, AOS6, delta4

DLL4 is altered in 0.00% of all cancers with breast invasive ductal carcinoma having the greatest prevalence of alterations [3].

DLL4 GENIE Cases - Top Diseases

The most common alteration in DLL4 is DLL4-RAD51 Fusion (0.00%) [3].

DLL4 GENIE Cases - Top Alterations

Significance of DLL4 in Diseases

Breast Carcinoma +

Cholangiocarcinoma +

Colon Carcinoma +

Lymphoma +

Malignant Solid Tumor +

Soft Tissue Sarcoma +


1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.