DNMT3B is altered in 1.90% of all cancers with colon adenocarcinoma, lung adenocarcinoma, endometrial endometrioid adenocarcinoma, cutaneous melanoma, and rectal adenocarcinoma having the greatest prevalence of alterations .
The most common alterations in DNMT3B are DNMT3B Mutation (1.07%), DNMT3B Amplification (0.69%), DNMT3B E674K (0.02%), DNMT3B A241T (0.01%), and DNMT3B Loss (0.01%) .
2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.
3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.