Associated Genetic Biomarkers
Associated Diseases


Location [1]
Protein [2]
Eukaryotic translation initiation factor 1A, X-chromosomal
Synonyms [1]

EIF1AX is altered in 1.21% of all cancers with high grade ovarian serous adenocarcinoma, lung adenocarcinoma, uveal melanoma, breast invasive ductal carcinoma, and prostate adenocarcinoma having the greatest prevalence of alterations [3].

EIF1AX GENIE Cases - Top Diseases

The most common alterations in EIF1AX are EIF1AX Mutation (0.51%), EIF1AX Loss (0.48%), EIF1AX Amplification (0.16%), EIF1AX X113_splice (0.06%), and EIF1AX R13H (0.04%) [3].

EIF1AX GENIE Cases - Top Alterations


1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015.

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.