Location [1]
Protein [2]
Eukaryotic translation initiation factor 3 subunit E
Synonyms [1]
EIF3S6, EIF3-P48, INT6, eIF3-p46

EIF3E is altered in 0.13% of all cancers with high grade ovarian serous adenocarcinoma, bladder urothelial carcinoma, breast invasive ductal carcinoma, colon adenocarcinoma, and combined hepatocellular carcinoma and cholangiocarcinoma having the greatest prevalence of alterations [3].

EIF3E GENIE Cases - Top Diseases

The most common alteration in EIF3E is EIF3E-RSPO2 Fusion (0.13%) [3].

EIF3E GENIE Cases - Top Alterations


1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.