Biomarkers /

ELF3

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Associated Diseases

Overview

Location [1]
1q32.1
Protein [2]
ETS-related transcription factor Elf-3
Synonyms [1]
ESX, EPR-1, ESE-1, ERT

ELF3 is altered in 2.80% of all cancers with breast invasive ductal carcinoma, bladder urothelial carcinoma, lung adenocarcinoma, colon adenocarcinoma, and invasive breast carcinoma having the greatest prevalence of alterations [3].

ELF3 GENIE Cases - Top Diseases

The most common alterations in ELF3 are ELF3 Amplification (1.42%), ELF3 Mutation (0.81%), ELF3 Loss (0.04%), ELF3 X160_splice (0.02%), and ELF3 M324I (0.01%) [3].

ELF3 GENIE Cases - Top Alterations

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.