Location [1]
Protein [2]
Nucleotide pyrophosphatase
Synonyms [1]
NPP3, PD-IBETA, CD203c, B10, PDNP3

ENPP3 is altered in 0.02% of all cancers with lung adenocarcinoma having the greatest prevalence of alterations [3].

ENPP3 GENIE Cases - Top Diseases

The most common alteration in ENPP3 is ENPP3-RSPO3 Fusion (0.02%) [3].

ENPP3 GENIE Cases - Top Alterations

Significance of ENPP3 in Diseases

Clear Cell Renal Cell Carcinoma +

Renal Cell Carcinoma +


1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.