Biomarkers /
ETV4
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Overview
ETS variant 4 (ETV4) is a gene that encodes a transcription factor protein that is a member of the ETS (E twenty-six) family. The protein functions in the regulation of cell growth, angiogenesis, migration proliferation, and differentiation. Fusions, missense mutations, and silent mutations are observed in cancers such as ovarian cancer and cancers of the upper digestive tract.
Clinical Trials
Significance of ETV4 in Diseases
References
1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta
2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.
3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.
4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.
