Location [1]
Protein [2]
Pre-mRNA 3'-end-processing factor FIP1
Synonyms [1]
FIP1, Rhe, hFip1

FIP1L1 is altered in 0.38% of all cancers with glioblastoma, lung adenocarcinoma, conventional glioblastoma multiforme, invasive breast carcinoma, and breast invasive ductal carcinoma having the greatest prevalence of alterations [3].

FIP1L1 GENIE Cases - Top Diseases

The most common alterations in FIP1L1 are FIP1L1-PDGFRA Fusion (0.18%), FIP1L1 Mutation (0.36%), FIP1L1-RARA Fusion (0.10%), FIP1L1 Fusion (0.07%), and FIP1L1 E303K (0.04%) [3].

FIP1L1 GENIE Cases - Top Alterations


1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.