Biomarkers /

HIST1H2BD

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Overview

Location [1]
6p22.2
Protein [2]
Histone H2B type 1-D
Synonyms [1]
HIRIP2, dJ221C16.6, H2B/b, H2BFB, H2B.1B

HIST1H2BD is altered in 0.59% of all cancers with lung adenocarcinoma, breast invasive ductal carcinoma, colon adenocarcinoma, bladder urothelial carcinoma, and diffuse large B-cell lymphoma, not otherwise specified having the greatest prevalence of alterations [3].

HIST1H2BD GENIE Cases - Top Diseases

The most common alterations in HIST1H2BD are HIST1H2BD Amplification (0.14%), HIST1H2BD Loss (0.12%), HIST1H2BD E77K (0.02%), HIST1H2BD Y43C (0.02%), and HIST1H2BD E72Q (0.02%) [3].

HIST1H2BD GENIE Cases - Top Alterations

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.