Overview

Location [1]
6p22.2
Synonyms [1]
H3.1, H3/d, H3FD

HIST1H3E is altered in 0.58% of all cancers with colon adenocarcinoma, lung adenocarcinoma, breast invasive ductal carcinoma, endometrial endometrioid adenocarcinoma, and pancreatic adenocarcinoma having the greatest prevalence of alterations [3].

HIST1H3E GENIE Cases - Top Diseases

The most common alterations in HIST1H3E are HIST1H3E Amplification (0.14%), HIST1H3E Loss (0.13%), HIST1H3E A136V (0.01%), HIST1H3E A92V (0.01%), and HIST1H3E E60K (0.01%) [3].

HIST1H3E GENIE Cases - Top Alterations

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.