Overview

Location [1]
Xp22.33 and Yp11.2
Protein [2]
Interleukin-3 receptor subunit alpha
Synonyms [1]
IL3R, IL3RAY, hIL-3Ra, CD123, IL3RY, IL3RX

Significance of IL3RA in Diseases

Acute Myeloid Leukemia +

Blastic Plasmacytoid Dendritic Cell Neoplasm +

Acute Lymphoblastic Leukemia +

B-Cell Acute Lymphoblastic Leukemia +

Chronic Myeloid Leukemia +

Myelodysplastic Syndromes +

Acute Biphenotypic Leukemia +

Acute Promyelocytic Leukemia +

Chronic Myelomonocytic Leukemia +

Hematopoietic And Lymphoid Malignancy +

Myeloproliferative Neoplasm +

Refractory Hematologic Malignancy +

Systemic Mastocytosis +

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.