Associated Genetic Biomarkers
Associated Diseases


Location [1]
Protein [2]
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2
Synonyms [1]

INPPL1 is altered in 0.64% of all cancers with breast invasive ductal carcinoma, invasive breast carcinoma, and breast invasive lobular carcinoma having the greatest prevalence of alterations [3].

INPPL1 GENIE Cases - Top Diseases

The most common alterations in INPPL1 are INPPL1 Amplification (0.17%) and INPPL1 Loss (0.04%) [3].

INPPL1 GENIE Cases - Top Alterations

Significance of INPPL1 in Diseases

Malignant Solid Tumor +


1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015.

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.