Associated Genetic Biomarkers
Associated Diseases

Overview

Location [1]
1p35.2
Protein [2]
Tyrosine-protein kinase Lck
Synonyms [1]
YT16, p56lck, pp58lck, LSK, IMD22

LCK is altered in 0.86% of all cancers.

The most common alterations in LCK are LCK Mutation (0.02%), LCK D496Y (0.00%), LCK G85V (0.00%), LCK K401M (0.00%), and LCK L88H (0.00%) [3].

LCK GENIE Cases - Top Alterations

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.