Overview

MAGEA8 is altered in 1.90% of all cancers with breast invasive ductal carcinoma, breast invasive lobular carcinoma, breast neoplasm, and mucinous breast carcinoma having the greatest prevalence of alterations [3].

The most common alterations in MAGEA8 are MAGEA8 Amplification (1.24%), MAGEA8 A264V (0.08%), MAGEA8 L139F (0.08%), MAGEA8 Loss (0.08%), and MAGEA8 D113H (0.04%) [3].

Significance of MAGEA8 in Diseases

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.