Overview

Location [1]
10q26.3
Protein [2]
Methylated-DNA--protein-cysteine methyltransferase
Synonyms [1]
-

MGMT is altered in 0.07% of all cancers.

The most common alterations in MGMT are MGMT Mutation (0.01%), MGMT L19F (0.00%), MGMT A12A (0.00%), MGMT C25G (0.00%), and MGMT L8L (0.00%) [3].

MGMT GENIE Cases - Top Alterations

Significance of MGMT in Diseases

Breast Carcinoma +

Colorectal Adenocarcinoma +

Glioblastoma +

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.