Overview

Location [1]
3q25.2
Protein [2]
Neprilysin
Synonyms [1]
CALLA, CD10, NEP, SCA43, CMT2T, SFE

Significance of MME in Diseases

Diffuse Large B-Cell Lymphoma +

Angioimmunoblastic T-Cell Lymphoma +

Diffuse Large B-Cell Lymphoma Activated B-Cell Type +

Follicular T-Cell Lymphoma +

Germinal Center B-Cell-Like Diffuse Large B-Cell Lymphoma +

Transformed Non-Hodgkin Lymphoma +

Acute Lymphoblastic Leukemia +

B-Cell Lymphoma, Unclassifiable, With Features Intermediate Between Diffuse Large B-Cell Lymphoma And Classical Hodgkin Lymphoma +

Diffuse Large B-Cell Lymphoma, Not Otherwise Specified +

Double-Hit Lymphoma +

Grade 3b Follicular Lymphoma +

High Grade B-Cell Lymphoma With MYC And BCL2 And/Or BCL6 Rearrangements +

High Grade B-Cell Lymphoma, Not Otherwise Specified +

Nodal Peripheral T-Cell Lymphoma With TFH Phenotype +

Peripheral T-Cell Lymphoma +

Primary Mediastinal B-Cell Lymphoma +

Triple-Hit Lymphoma +

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.