Overview

Location [1]
16p13.3
Protein [2]
Mesothelin, cleaved form
Synonyms [1]
SMRP, MPF

Significance of MSLN in Diseases

Non-Small Cell Lung Carcinoma +

Malignant Solid Tumor +

Malignant Pleural Mesothelioma +

Ovarian Carcinoma +

Pancreatic Adenocarcinoma +

Breast Carcinoma +

Mesothelioma +

Pleural Mesothelioma +

Fallopian Tube Carcinoma +

Hepatocellular Carcinoma +

Lung Adenocarcinoma +

Pancreatic Carcinoma +

Pancreatic Ductal Adenocarcinoma +

Peritoneal Mesothelioma +

Primary Peritoneal Carcinoma +

Cancer +

Cholangiocarcinoma +

Endometrial Carcinoma +

Epithelioid Mesothelioma +

Esophageal Carcinoma +

Extrahepatic Cholangiocarcinoma +

Gastric Carcinoma +

Glioblastoma +

High Grade Ovarian Serous Adenocarcinoma +

Malignant Leptomeningeal Neoplasm +

Malignant Ovarian Epithelial Tumor +

Ovarian Serous Adenocarcinoma +

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.