Biomarkers /

MST1

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Overview

Location [1]
3p21.31
Protein [2]
Hepatocyte growth factor-like protein beta chain
Synonyms [1]
MSP, D3F15S2, NF15S2, DNF15S2, HGFL

MST1 is altered in 0.19% of all cancers with colon adenocarcinoma, endometrial endometrioid adenocarcinoma, rectal adenocarcinoma, breast invasive ductal carcinoma, and cutaneous melanoma having the greatest prevalence of alterations [3].

MST1 GENIE Cases - Top Diseases

The most common alterations in MST1 are MST1 Loss (0.08%), MST1 Amplification (0.03%), MST1 S14N (0.01%), MST1 E92K (0.01%), and MST1 A114V (0.01%) [3].

MST1 GENIE Cases - Top Alterations

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.