Overview

Location [1]
11p15.1
Protein [2]
Myoblast determination protein 1
Synonyms [1]
MYF3, PUM, bHLHc1, MYODRIF, MYOD

MYOD1 is altered in 0.96% of all cancers with lung adenocarcinoma, colon adenocarcinoma, breast invasive ductal carcinoma, endometrial endometrioid adenocarcinoma, and bladder urothelial carcinoma having the greatest prevalence of alterations [3].

MYOD1 GENIE Cases - Top Diseases

The most common alterations in MYOD1 are MYOD1 Mutation (0.70%), MYOD1 Amplification (0.14%), MYOD1 Loss (0.08%), MYOD1 L122R (0.03%), and MYOD1 R120H (0.02%) [3].

MYOD1 GENIE Cases - Top Alterations

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.