Overview

Location [1]
8q13.3
Protein [2]
PR domain zinc finger protein 14
Synonyms [1]
PFM11

PRDM14 is altered in 2.66% of all cancers with prostate adenocarcinoma, breast invasive ductal carcinoma, lung adenocarcinoma, invasive breast carcinoma, and colon adenocarcinoma having the greatest prevalence of alterations [3].

PRDM14 GENIE Cases - Top Diseases

The most common alterations in PRDM14 are PRDM14 Amplification (1.43%), PRDM14 M565I (0.03%), PRDM14 Loss (0.02%), PRDM14 S475N (0.02%), and PRDM14 R439Q (0.02%) [3].

PRDM14 GENIE Cases - Top Alterations

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.