Associated Genetic Biomarkers
Associated Diseases

Overview

Location [1]
17q24.2
Protein [2]
Protein kinase C alpha type
Synonyms [1]
PRKACA, PKCalpha, AAG6, PKCI+/-, PKCA, PKC-alpha

PRKCA is altered in 0.04% of all cancers.

Significance of PRKCA in Diseases

Colorectal Carcinoma +

Cutaneous Melanoma +

Malignant Solid Tumor +

Uveal Melanoma +

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.