Associated Genetic Biomarkers
Associated Diseases


Location [1]
Protein [2]
Protein kinase C beta type
Synonyms [1]
PKCB, PKC-beta, PKCbeta, PKCI(2), PRKCB2, PRKCB1

PRKCB is altered in 0.06% of all cancers with non-small cell lung carcinoma having the greatest prevalence of alterations [3].

PRKCB GENIE Cases - Top Diseases

The most common alteration in PRKCB is PRKCB Fusion (0.06%) [3].

PRKCB GENIE Cases - Top Alterations

Significance of PRKCB in Diseases

Colorectal Carcinoma +

Cutaneous Melanoma +

Malignant Solid Tumor +

Uveal Melanoma +


1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015.

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.