Associated Genetic Biomarkers
Associated Diseases

Overview

Location [1]
10p15.1
Protein [2]
Protein kinase C theta type
Synonyms [1]
PRKCT, nPKC-theta

PRKCQ is altered in 4.05% of all cancers with breast invasive ductal carcinoma having the greatest prevalence of alterations [3].

PRKCQ GENIE Cases - Top Diseases

The most common alteration in PRKCQ is PRKCQ Amplification (0.23%) [3].

PRKCQ GENIE Cases - Top Alterations

Significance of PRKCQ in Diseases

Malignant Solid Tumor +

Colorectal Carcinoma +

Cutaneous Melanoma +

Uveal Melanoma +

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.