Overview

Location [1]
5q33.3
Protein [2]
Securin
Synonyms [1]
HPTTG, TUTR1, EAP1, PTTG

PTTG1 is altered in 0.30% of all cancers with skin squamous cell carcinoma having the greatest prevalence of alterations [3].

PTTG1 GENIE Cases - Top Diseases

Significance of PTTG1 in Diseases

Malignant Solid Tumor +

Chronic Lymphocytic Leukemia +

Hodgkin Lymphoma +

Multiple Myeloma +

Non-Hodgkin Lymphoma +

Acute Lymphoblastic Leukemia +

Acute Myeloid Leukemia +

Chronic Myeloid Leukemia +

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.