Biomarkers /

ROR1

Back to Biomarkers List
Associated Genetic Biomarkers
Associated Diseases

Overview

Location [1]
1p31.3
Protein [2]
Inactive tyrosine-protein kinase transmembrane receptor ROR1
Synonyms [1]
NTRKR1, dJ537F10.1

ROR1 is altered in 0.01% of all cancers with esophageal adenocarcinoma and gastric adenocarcinoma having the greatest prevalence of alterations [3].

ROR1 GENIE Cases - Top Diseases

The most common alterations in ROR1 are ROR1-FOXO1 Fusion (0.02%) and ROR1-LINC00910 Fusion (0.01%) [3].

ROR1 GENIE Cases - Top Alterations

Clinical Trials

View Clinical Trials for ROR1

Significance of ROR1 in Diseases

Acute Lymphoblastic Leukemia +

Breast Carcinoma +

Chronic Lymphocytic Leukemia +

Mantle Cell Lymphoma +

Non-Small Cell Lung Carcinoma +

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.