Location [1]
Protein [2]
Replication protein A 32 kDa subunit
Synonyms [1]
REPA2, "RP-A p34", RPA32, "RP-A p32"

RPA2 is altered in 0.26% of all cancers with invasive breast carcinoma having the greatest prevalence of alterations [3].

RPA2 GENIE Cases - Top Diseases

The most common alterations in RPA2 are RPA2 F194L (0.26%) and RPA2 Mutation (0.26%) [3].

RPA2 GENIE Cases - Top Alterations

Significance of RPA2 in Diseases

Breast Carcinoma +

Malignant Solid Tumor +

Adenocarcinoma Of The Gastroesophageal Junction +

Bile Duct Carcinoma +

Bladder Carcinoma +

Bronchogenic Carcinoma +

Cervical Carcinoma +

Colorectal Carcinoma +

Esophageal Squamous Cell Carcinoma +

Gallbladder Carcinoma +

Gastric Adenocarcinoma +

Head And Neck Carcinoma +

Lung Carcinoma +

Malignant Uterine Neoplasm +

Melanoma +

Non-Small Cell Lung Carcinoma +

Ovarian Carcinoma +

Pancreatic Carcinoma +

Soft Tissue Sarcoma +


1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.