Biomarkers /

SDHAF2

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Associated Genetic Biomarkers
Associated Diseases

Overview

Location [1]
11q12.2
Synonyms [1]
PGL2, C11orf79, SDH5

Succinate dehydrogenase complex assembly factor 2 (SDHAF2) is a gene that encodes a mitochondrial protein. Missense mutations, synonymous mutations, and frameshift insertions have been observed in cancers such as colon cancer, kidney cancer, and skin cancer.

Clinical Trials

View Clinical Trials for SDHAF2

Significance of SDHAF2 in Diseases

Gastrointestinal Stromal Tumor +

Leiomyosarcoma +

Malignant Solid Tumor +

Osteosarcoma +

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.