Location [1]
Protein [2]
Splicing factor, proline- and glutamine-rich
Synonyms [1]
PPP1R140, PSF, POMP100

SFPQ is altered in 0.02% of all cancers with pecoma, translocation-associated renal cell carcinoma, large cell neuroendocrine carcinoma, and lung adenocarcinoma having the greatest prevalence of alterations [3].

SFPQ GENIE Cases - Top Diseases

The most common alterations in SFPQ are SFPQ-TFE3 Fusion (0.01%) and SFPQ P188del (0.26%) [3].

SFPQ GENIE Cases - Top Alterations


1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.