Overview

Location [1]
3p13
Protein [2]
Protein SHQ1 homolog
Synonyms [1]
GRIM-1, Shq1p

SHQ1 is altered in 0.81% of all cancers with lung adenocarcinoma, colon adenocarcinoma, bladder urothelial carcinoma, endometrial endometrioid adenocarcinoma, and cutaneous melanoma having the greatest prevalence of alterations [3].

SHQ1 GENIE Cases - Top Diseases

The most common alterations in SHQ1 are SHQ1 Loss (0.10%), SHQ1 Amplification (0.10%), SHQ1 R154Q (0.01%), SHQ1 R75H (0.01%), and SHQ1 R160Q (0.03%) [3].

SHQ1 GENIE Cases - Top Alterations

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.