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SLC34A2

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Associated Diseases

Overview

Location [1]
4p15.2
Protein [2]
Sodium-dependent phosphate transport protein 2B
Synonyms [1]
NAPI-IIb, NPTIIb, NAPI-3B, PULAM

SLC34A2 is altered in 0.45% of all cancers with lung adenocarcinoma, colon adenocarcinoma, melanoma, breast invasive ductal carcinoma, and endometrial endometrioid adenocarcinoma having the greatest prevalence of alterations [3].

SLC34A2 GENIE Cases - Top Diseases

The most common alterations in SLC34A2 are SLC34A2-ROS1 Fusion (0.05%), SLC34A2 C687S (0.04%), SLC34A2 S318W (0.04%), SLC34A2 S461C (0.04%), and SLC34A2 T154A (0.04%) [3].

SLC34A2 GENIE Cases - Top Alterations

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.