Biomarkers /

SOX11

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Associated Diseases

Overview

Location [1]
2p25.2
Protein [2]
Transcription factor SOX-11
Synonyms [1]
MRD27, CSS9

SOX11 is altered in 1.34% of all cancers with high grade ovarian serous adenocarcinoma, colon adenocarcinoma, endometrial endometrioid adenocarcinoma, bladder urothelial carcinoma, and cancer, NOS having the greatest prevalence of alterations [3].

SOX11 GENIE Cases - Top Diseases

The most common alterations in SOX11 are SOX11 A175T (0.22%), SOX11 A277T (0.22%), SOX11 A28V (0.85%), SOX11 D227N (0.20%), and SOX11 E296K (0.22%) [3].

SOX11 GENIE Cases - Top Alterations

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.