Location [1]
Protein [2]
Transcription factor SOX-17
Synonyms [1]

SOX17 is altered in 2.73% of all cancers with colon adenocarcinoma, breast invasive ductal carcinoma, lung adenocarcinoma, prostate adenocarcinoma, and endometrial endometrioid adenocarcinoma having the greatest prevalence of alterations [3].

SOX17 GENIE Cases - Top Diseases

The most common alterations in SOX17 are SOX17 Amplification (1.12%), SOX17 Loss (0.07%), SOX17 A96G (0.03%), SOX17 A292T (0.02%), and SOX17 A108V (0.02%) [3].

SOX17 GENIE Cases - Top Alterations


1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.