Overview

Location [1]
17q25.1
Protein [2]
Somatostatin receptor type 2
Synonyms [1]
-

Biomarker-Directed Therapies

Significance of SSTR2 in Diseases

Pancreatic Neuroendocrine Tumor +

Small Intestinal Neuroendocrine Tumor +

Gastric Neuroendocrine Tumor +

Colorectal Neuroendocrine Tumor +

Esophageal Neuroendocrine Tumor +

Neuroendocrine Tumor +

Adrenal Gland Pheochromocytoma +

Paraganglioma +

Lung Neuroendocrine Neoplasm +

Neuroendocrine Carcinoma +

Colon Neuroendocrine Neoplasm +

Gastrointestinal Neuroendocrine Tumors +

Lung Carcinoid Tumor +

Malignant Solid Tumor +

Small Cell Lung Carcinoma +

Thyroid Gland Medullary Carcinoma +

Appendix Neuroendocrine Tumor +

Breast Carcinoma +

Colorectal Neuroendocrine Neoplasm +

Digestive System Neuroendocrine Neoplasm +

Functional Pancreatic Neuroendocrine Tumor +

Grade I Meningioma +

Grade II Meningioma +

Grade III Meningioma +

Large Cell Lung Neuroendocrine Carcinoma +

Meningioma +

Merkel Cell Carcinoma +

Neuroblastoma +

Neuroendocrine Carcinoma Of Unknown Primary +

Neuroendocrine Tumor, NOS +

Non-Functioning Pancreatic Endocrine Tumor +

Parathyroid Gland Carcinoma +

Pituitary Gland Carcinoma +

Rectal Neuroendocrine Tumor +

Thymic Carcinoid Tumor +

Thymic Neuroendocrine Neoplasm +

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.