Associated Genetic Biomarkers
Associated Diseases

Overview

Location [1]
Xp11.22
Protein [2]
Protein SSX2
Synonyms [1]
HOM-MEL-40, SSX, CT5.2, CT5.2b

SSX2B is altered in 0.05% of all cancers with pancreatic adenocarcinoma, breast invasive ductal carcinoma, esophagogastric carcinoma, invasive breast carcinoma, and papillary renal cell carcinoma having the greatest prevalence of alterations [3].

SSX2B GENIE Cases - Top Diseases

Significance of SSX2B in Diseases

Synovial Sarcoma +

Bladder Carcinoma +

Breast Carcinoma +

Endometrial Endometrioid Adenocarcinoma +

Epithelioid Sarcoma +

Malignant Ovarian Clear Cell Tumor +

Malignant Ovarian Endometrioid Tumor +

Malignant Solid Tumor +

Rhabdoid Tumor +

Sarcomatoid Carcinoma +

Soft Tissue Sarcoma +

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.