Biomarkers /

STK19

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Associated Diseases

Overview

Location [1]
6p21.33
Protein [2]
Serine/threonine-protein kinase 19
Synonyms [1]
D6S60, RP1, HLA-RP1, G11, D6S60E

STK19 is altered in 0.79% of all cancers with cutaneous melanoma, lung adenocarcinoma, colon adenocarcinoma, breast invasive ductal carcinoma, and endometrial endometrioid adenocarcinoma having the greatest prevalence of alterations [3].

STK19 GENIE Cases - Top Diseases

The most common alterations in STK19 are STK19 Mutation (0.61%), STK19 Amplification (0.14%), STK19 D89N (0.11%), STK19 E88K (0.03%), and STK19 Loss (0.03%) [3].

STK19 GENIE Cases - Top Alterations

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.