Location [1]
Protein [2]
Transforming acidic coiled-coil-containing protein 1
Synonyms [1]

TACC1 is altered in 0.08% of all cancers with breast invasive ductal carcinoma, colon adenocarcinoma, bladder urothelial carcinoma, dysembryoplastic neuroepithelial tumor, and high grade ovarian serous adenocarcinoma having the greatest prevalence of alterations [3].

TACC1 GENIE Cases - Top Diseases

The most common alterations in TACC1 are TACC1-FGFR1 Fusion (0.02%), TACC1-CYLD Fusion (0.00%), TACC1-INSR Fusion (0.00%), and TACC1-WHSC1L1 Fusion (0.00%) [3].

TACC1 GENIE Cases - Top Alterations

Significance of TACC1 in Diseases

Glioma +


1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.