TGFBR2
Transforming growth factor, beta receptor II (TGFBR2) is a gene that encodes a protein that functions as serine/threonine kinase and TGF-beta receptor. The protein receptor binds TGF-beta to ultimately regulate transcription and cell proliferation. Missense mutations, nonsense mutations, silent mutations, frameshift deletions and insertions, and in-frame deletions are observed in cancers such as endometrial cancer, intestinal cancer, and stomach cancer.