Biomarkers /

TRAF7

Back to Biomarkers List

Overview

Location [1]
16p13.3
Protein [2]
E3 ubiquitin-protein ligase TRAF7
Synonyms [1]
RFWD1, RNF119, CAFDADD

TRAF7 is altered in 1.41% of all cancers with lung adenocarcinoma, colon adenocarcinoma, breast invasive ductal carcinoma, cutaneous melanoma, and meningioma having the greatest prevalence of alterations [3].

TRAF7 GENIE Cases - Top Diseases

The most common alterations in TRAF7 are TRAF7 Amplification (0.17%), TRAF7 Loss (0.07%), TRAF7 Fusion (0.21%), TRAF7 G536S (0.02%), and TRAF7 R641H (0.03%) [3].

TRAF7 GENIE Cases - Top Alterations

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.