Location [1]
Synonyms [1]

TRB is altered in 0.01% of all cancers with T-cell lymphoblastic leukemia/lymphoma having the greatest prevalence of alterations [3].

TRB GENIE Cases - Top Diseases

The most common alterations in TRB are TRB Fusion (0.01%) and TRB-TAL2 Fusion (0.01%) [3].

TRB GENIE Cases - Top Alterations

Significance of TRB in Diseases

Acute Lymphoblastic Leukemia +

Acute Myeloid Leukemia +

B-Cell Acute Lymphoblastic Leukemia +

Myelodysplastic Syndromes +


1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.