Overview

Location [1]
7p14.1
Synonyms [1]
TCRG, TRG@

T cell receptor gamma locus (TRG) is a gene that encodes a protein that functions by recognizing foreign antigens that have been bound to major histocompatibility complex molecules at the surface of antigen presenting cells. Amplification has been observed in prostate cancer.

Significance of TRG in Diseases

Acute Lymphoblastic Leukemia +

Acute Myeloid Leukemia +

B-Cell Acute Lymphoblastic Leukemia +

Myelodysplastic Syndromes +

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20170629. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 4. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.