.accordion-toggle-area {
  line-height: 4em;
  text-align: left;
  padding-left: 2.5rem;
  padding-right: 2.5rem;
  cursor: pointer;
  margin-top: 2px;
  margin-bottom: 0;
}
.accordion-toggle-area-target {
  padding-left: 2.5em;
  padding-right: 2.5em;
  padding-top: 0.5em;
  border: 0.05em solid #007BC3;
  border-top: 0;
  margin-top: 0;
}

.associated-links-section {
  margin-left: 2em;
}

.arrow {
  border: solid black;
  border-width: 0 1px 1px 0;
  display: inline-block;
  padding: 3px;
  margin-right: 2em;
  cursor: pointer;
  margin-bottom: 0.2em;
}

.arrow.right {
  transform: rotate(-45deg);
  -webkit-transform: rotate(-45deg);
}

.arrow.down {
  transform: rotate(45deg);
  -webkit-transform: rotate(45deg);
}

.arrow.header {
  margin-right: 0.25em;
}

.clickable {
  cursor: pointer
}

.biomarker-disease-contents table {
  border: 1px solid #c8c8c8;
  border-spacing: 0;
}

.biomarker-disease-contents table tr th {
  text-align: left;
  background: #f1f1f1;
  border: 1px solid #c8c8c8;
}

.biomarker-disease-contents table tr td {
  background: white;
  border: 1px solid #c8c8c8;
}

.graph-header {
  font-weight: bold;
  padding-left: 4em;
}

.row.inner-row, .row.table-row {
  margin-left: 0;
  margin-right: 0;
  margin-bottom: 0.5rem;
}

.row.table-row {
  border-bottom: 2px solid grey;
  margin-bottom: 0;
}

.row.inner-row > div {
  padding-left: 0;
  padding-right: 0;
}

h4.split-header {
  margin-bottom: 0;
}

.underline-hover:hover {
  text-decoration: underline;
}

.indicator {
  float: right;
  font-size: 1.5em;
  font-family: monospace;
}

.about-alteration-disease-header,
.about-alteration-therapy-disease-header,
.about-gene-disease-header,
.about-gene-therapy-disease-header,
.about-disease-gene-header,
.about-disease-therapy-sensitivity-header,
.about-drug-therapy-sensitivity-header {
  background-color: #A5BDCF;
  color: white;
  line-height: 4em;
  text-align: left;
  padding-left: 2.5rem;
  padding-right: 2.5rem;
  cursor: pointer;
  margin-top: 2px;
  margin-bottom: 0;
}

.about-alteration-therapy-disease-header,
.about-gene-therapy-disease-header,
.about-disease-therapy-sensitivity-header,
.about-drug-therapy-sensitivity-header {
  margin-top: 0;
}

.about-alteration-disease-content,
.about-gene-disease-content,
.about-disease-gene-content {
  padding-left: 2.5em;
  padding-right: 2.5em;
  padding-top: 0.5em;
  margin-top: 0;
}

.about-alteration-therapy-header,
.about-gene-therapy-header,
.about-disease-therapy-header,
.about-drug-therapy-header {
  line-height: 4em;
  text-align: left;
  padding-left: 1rem;
  padding-right: 2.5rem;
  cursor: pointer;
  margin-top: 2px;
  margin-bottom: 0;
  border: 0.05em solid #007BC3;
  border-left: 1.5em solid #153547;
}

.about-alteration-therapy-disease-content,
.about-gene-therapy-disease-content,
.about-disease-therapy-sensitivity-content,
.about-drug-therapy-sensitivity-content {
  margin-left: 0 !important;
  margin-right: 0 !important;
  border-top: none;
  border-right: 0.05em solid #007BC3;
  border-left: 0.1em solid #153547;
}

.description-title {
  color: #007BC3;
}

.response-setting-note > div:not(:last-child) {
  border-bottom: 2px solid #cecece
}

.biomarker-criteria, .response-setting-note > div > div {
  padding-top: 0.5rem;
  padding-bottom: 0.5rem;
}

.biomarker-criteria {
  border-bottom: 2px solid #cecece;
}

.therapy_criteria {
  padding-left: 1.5em;
}

.therapy_criteria_header {
  padding-left: 0em;
}

/*
Abandon hope, all ye who enter here.

On a more serious note, the following styling is borrowed from Foundation's documentation [1] to handle the different
layouts for the Targeted Therapy tables at different screen sizes.

[1] https://foundation.zurb.com/sites/docs/v/5.5.3/media-queries.html
*/

@media only screen { /* Define mobile styles */
  div.targeted-therapy-table-small-screen-container {
    display: block;
  }

  div.targeted-therapy-table-large-screen-container {
    display: none;
  }
}

@media only screen and (min-width: 64.063em) { /* min-width 1025px, large screens */
  div.targeted-therapy-table-small-screen-container {
    display: none;
  }

  div.targeted-therapy-table-large-screen-container {
    display: block;
  }
}

/*
Regain hope.
*/

/* undo foundation table styling */
table.targeted-therapy-table-large-screen tr:nth-child(even) {
  background-color: inherit;
}

table.targeted-therapy-table-large-screen td {
  vertical-align: top;
}

table.targeted-therapy-table-large-screen td.left-column {
  border-bottom: 2px solid #cecece;
}

table.targeted-therapy-table-large-screen td.left-column.last {
  border-bottom: 0;
}

table.targeted-therapy-table-large-screen td.right-column {
  border-right: 2px solid #cecece;
  width: 33.33%;
}

table.targeted-therapy-table-large-screen {
  border-collapse: collapse;
  margin-bottom: 0;
}

div.targeted-therapy-table-large-screen-container {
  border-bottom: 2px solid grey;
}

.section-spacing {
  margin-bottom: 1rem;
}

div.bokeh-container {
  height: 0;
  overflow: hidden;
  padding-top: 80%;
  position: relative;
}

div.bokeh-container > div.bk-root {
  position: absolute;
  top: 0;
  left: 0;
  width: 100%;
  height: 100%;
}