ALK Codon 1174 Missense
Associated Genetic Biomarkers
ALK Codon 1174 Missense is present in 0.02% of AACR GENIE cases, with neuroblastoma having the greatest prevalence .
ALK Codon 1174 Missense serves as an inclusion eligibility criterion in 1 clinical trial, of which 1 is open and 0 are closed. Of the trial that contains ALK Codon 1174 Missense as an inclusion criterion, 1 is phase 2 (1 open).
Trials with ALK Codon 1174 Missense in the inclusion eligibility criteria most commonly target non-small cell lung carcinoma .
Crizotinib and lorlatinib are the most frequent therapies in trials with ALK Codon 1174 Missense as an inclusion criteria .
Significance of ALK Codon 1174 Missense in Diseases
Non-Small Cell Lung Carcinoma +
ALK is altered in 4.47% of non-small cell lung carcinoma patients .
ALK Codon 1174 Missense is an inclusion criterion in 1 clinical trial for non-small cell lung carcinoma, of which 1 is open and 0 are closed. Of the trial that contains ALK Codon 1174 Missense and non-small cell lung carcinoma as inclusion criteria, 1 is phase 2 (1 open) .
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