BRAF Codon 599 Missense
Associated Genetic Biomarkers
BRAF Codon 599 Missense is present in 0.02% of AACR GENIE cases, with bladder urothelial carcinoma and pancreatic neuroendocrine neoplasm having the greatest prevalence .
BRAF Codon 599 Missense serves as an inclusion eligibility criterion in 1 clinical trial, of which 1 is open and 0 are closed. Of the trial that contains BRAF Codon 599 Missense as an inclusion criterion, 1 is phase 2 (1 open).
Trials with BRAF Codon 599 Missense in the inclusion eligibility criteria most commonly target malignant solid tumor and melanoma .
Binimetinib and encorafenib are the most frequent therapies in trials with BRAF Codon 599 Missense as an inclusion criteria .
Significance of BRAF Codon 599 Missense in Diseases
Malignant Solid Tumor +
BRAF is altered in 6.59% of malignant solid tumor patients with BRAF Codon 599 Missense present in 0.0% of all malignant solid tumor patients .
BRAF Codon 599 Missense is an inclusion criterion in 1 clinical trial for malignant solid tumor, of which 1 is open and 0 are closed. Of the trial that contains BRAF Codon 599 Missense and malignant solid tumor as inclusion criteria, 1 is phase 2 (1 open) .
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