Associated Genetic Biomarkers
BRAF D594E is present in 0.01% of AACR GENIE cases, with bladder carcinoma, colorectal adenocarcinoma, gastric adenocarcinoma, leukemia, and melanoma having the greatest prevalence .
BRAF D594E serves as an inclusion eligibility criterion in 1 clinical trial, of which 0 are open and 1 is closed. Of the trial that contains BRAF D594E as an inclusion criterion, 1 is phase 1 (0 open).
Trials with BRAF D594E in the inclusion eligibility criteria most commonly target malignant solid tumor and non-small cell lung carcinoma .
Significance of BRAF D594E in Diseases
Malignant Solid Tumor +
BRAF is mutated in 39.82% of malignant solid tumor patients with BRAF D594E present in 0.11% of all malignant solid tumor patients .
BRAF D594E is an inclusion criterion in 1 clinical trial for malignant solid tumor, of which 0 are open and 1 is closed. Of the trial that contains BRAF D594E and malignant solid tumor as inclusion criteria, 1 is phase 1 (0 open) .
Non-Small Cell Lung Carcinoma +
BRAF is mutated in 5.34% of non-small cell lung carcinoma patients with BRAF D594E present in 0.01% of all non-small cell lung carcinoma patients .
BRAF D594E is an inclusion criterion in 1 clinical trial for non-small cell lung carcinoma, of which 0 are open and 1 is closed. Of the trial that contains BRAF D594E and non-small cell lung carcinoma as inclusion criteria, 1 is phase 1 (0 open) .
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