Associated Genetic Biomarkers
BRAF G466E is present in 0.05% of AACR GENIE cases, with melanoma, non-small cell lung carcinoma, colorectal adenocarcinoma, adenocarcinoma of unknown primary, and malignant glioma having the greatest prevalence .
BRAF G466E serves as an inclusion eligibility criterion in 1 clinical trial, of which 1 is open and 0 are closed. Of the trial that contains BRAF G466E as an inclusion criterion, 1 is phase 1 (1 open).
Trials with BRAF G466E in the inclusion eligibility criteria most commonly target malignant solid tumor .
Rmc-4630 is the most frequent therapy in trials with BRAF G466E as an inclusion criteria .
Significance of BRAF G466E in Diseases
Malignant Solid Tumor +
BRAF is mutated in 39.82% of malignant solid tumor patients with BRAF G466E present in 0.44% of all malignant solid tumor patients .
BRAF G466E is an inclusion criterion in 1 clinical trial for malignant solid tumor, of which 1 is open and 0 are closed. Of the trial that contains BRAF G466E and malignant solid tumor as inclusion criteria, 1 is phase 1 (1 open) .
Rmc-4630 is the most frequent therapy in trials for malignant solid tumor that contain BRAF G466E .
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