Associated Genetic Biomarkers
CDKN2C Mutation is present in 0.35% of AACR GENIE cases, with lung adenocarcinoma, colon adenocarcinoma, conventional glioblastoma multiforme, endometrial endometrioid adenocarcinoma, and glioblastoma having the greatest prevalence .
CDKN2C Mutation serves as an inclusion eligibility criterion in 1 clinical trial, of which 1 is open and 0 are closed. Of the trial that contains CDKN2C Mutation as an inclusion criterion, 1 is phase 1/phase 2 (1 open).
Trials with CDKN2C Mutation in the inclusion eligibility criteria most commonly target multiple myeloma .
Abemaciclib, dexamethasone, ixazomib, and pomalidomide are the most frequent therapies in trials with CDKN2C Mutation as an inclusion criteria .
Significance of CDKN2C Mutation in Diseases
Multiple Myeloma +
CDKN2C is altered in 2.38% of multiple myeloma patients .
CDKN2C Mutation is an inclusion criterion in 1 clinical trial for multiple myeloma, of which 1 is open and 0 are closed. Of the trial that contains CDKN2C Mutation and multiple myeloma as inclusion criteria, 1 is phase 1/phase 2 (1 open) .
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