Associated Genetic Biomarkers
PAX8-PPARG Fusion is present in 0.01% of AACR GENIE cases, with breast invasive ductal carcinoma, invasive breast carcinoma, salivary gland adenoid cystic carcinoma, and thyroid gland papillary carcinoma having the greatest prevalence .
PAX8-PPARG Fusion serves as an inclusion eligibility criterion in 1 clinical trial, of which 0 are open and 1 is closed. Of the trial that contains PAX8-PPARG Fusion as an inclusion criterion, 1 is phase 2 (0 open).
Significance of PAX8-PPARG Fusion in Diseases
Thyroid Gland Carcinoma +
PAX8-PPARG Fusion is an inclusion criterion in 1 clinical trial for thyroid gland carcinoma, of which 0 are open and 1 is closed. Of the trial that contains PAX8-PPARG Fusion and thyroid gland carcinoma as inclusion criteria, 1 is phase 2 (0 open) .
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4. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.