Overview

Variant Type
Expression

Significance of PD-L1 Expression (CPS >= 10) in Diseases

Gastric Carcinoma +

Bladder Urothelial Carcinoma +

Breast Carcinoma +

Cervical Carcinoma +

Esophageal Squamous Cell Carcinoma +

Head And Neck Squamous Cell Carcinoma +

Malignant Solid Tumor +

Melanoma +

Non-Small Cell Lung Carcinoma +

Urethral Urothelial Carcinoma +

Urothelial Carcinoma +

Adenocarcinoma Of The Gastroesophageal Junction +

Hepatocellular Carcinoma +

Hodgkin Lymphoma +

Invasive Breast Carcinoma +

Merkel Cell Carcinoma +

Primary Mediastinal B-Cell Lymphoma +

Renal Cell Carcinoma +

Renal Pelvis Urothelial Carcinoma +

Renal Pelvis And Ureter Urothelial Carcinoma +

Small Cell Lung Carcinoma +

Transitional Cell Carcinoma +

Ureter Urothelial Carcinoma +

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. Liu X, Wu C, Li C, and Boerwinkle E. dbNSFP v3.0: A one-stop database of functional predictions and annotations for human nonsynonymous and splice site SNVs. Human Mutation. 2015;37:235-241.

Liu X, Jian X, and Boerwinkle E. dbNSFP: A lightweight database of human nonsynonymous SNPs and their functional predictions. Human Mutation. 2011;32:894-899.

4. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

5. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.