Overview

NCI Definition: A T-cell peripheral lymphoma morphologically indistinguishable from anaplastic large cell lymphoma, ALK-positive. It is characterized by the absence of the translocation involving the ALK gene and lacks expression of ALK fusion protein. [1]

Significant Genes in Anaplastic Large Cell Lymphoma, ALK-Negative

ALK +

Disease Details

Synonyms
ALCL, ALK-, ALK-Negative Anaplastic Large Cell Lymphoma, Anaplastic Large Cell Lymphoma ALK Negative
Parent(s)
Anaplastic Large Cell Lymphoma
Children
Breast Implant-Associated Anaplastic Large Cell Lymphoma
OncoTree Name
Anaplastic Large-Cell Lymphoma ALK Negative
OncoTree Code
ALCLALKN

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.