Overview

NCI Definition: A mature T-cell non-Hodgkin lymphoma, characterized by systemic disease and a polymorphous infiltrate involving lymph nodes and extranodal sites. The clinical course is typically aggressive. [1]

Significant Genes in Angioimmunoblastic T-Cell Lymphoma

ALK +

BIRC2 +

BIRC3 +

CARD11 +

CD79A +

CD79B +

FLT3 +

IDH2 +

NFKBIA +

TNFAIP3 +

Disease Details

Synonyms
Angioimmunoblastic Lymphadenopathy, angioimmunoblastic T-cell lymphoma, Angioimmunoblastic Lymphadenopathy with Dysproteinemia, Angioimmunoblastic Lymphadenopathy Type T-Cell Lymphoma, AILT, AILD
Parent(s)
Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma
OncoTree Name
Angioimmunoblastic T-Cell Lymphoma
OncoTree Code
AITL

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.